As climate changes continues, the permafrost is thawing and releasing ancient viruses that has the potential to really hurt us. The risk is low, but plausible.
https://edition.cnn.com/2023/03/08/world/permafrost-virus-risk-climate-scn/index.html
https://edition.cnn.com/2023/03/08/world/permafrost-virus-risk-climate-scn/index.html